发明授权
US06177591B1 Optically active phosphine oxide carboxylic acid and method of producing the same 失效
光活性氧化膦羧酸及其制备方法

  • 专利标题: Optically active phosphine oxide carboxylic acid and method of producing the same
  • 专利标题(中): 光活性氧化膦羧酸及其制备方法
  • 申请号: US09371050
    申请日: 1999-08-10
  • 公开(公告)号: US06177591B1
    公开(公告)日: 2001-01-23
  • 发明人: Masashi SugiyaHiroyuki Nohira
  • 申请人: Masashi SugiyaHiroyuki Nohira
  • 主分类号: C07B5700
  • IPC分类号: C07B5700
Optically active phosphine oxide carboxylic acid and method of producing the same
摘要:
An optically active 1-phenylethylamine is reacted to a phosphine oxide carboxylic acid of a racemic modification shown by the following general formula (2): and a produced diastereomeric salt is separated using the difference in solubility against a solvent, which is subsequently decomposed by acid, so as to free and separate an optically active phosphine oxide carboxylic acid.
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