发明授权
- 专利标题: Trangenic mice with a disruption in the tiar gene
- 专利标题(中): 转基因小鼠在tiar基因中断
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申请号: US09039999申请日: 1998-03-17
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公开(公告)号: US06180849B2公开(公告)日: 2001-01-30
- 发明人: Michel Streuli , Paul Anderson , Andreas Beck
- 申请人: Michel Streuli , Paul Anderson , Andreas Beck
- 主分类号: C12N1585
- IPC分类号: C12N1585
摘要:
The invention features transgenic non-human mammals containing a mutation in one or both alleles of the endogenous TIAR gene, and cell lines derived from some of these mammals. The mammals and cell lines of the invention can be employed to identify compounds useful in treating infertility, obesity, neurological disorders, and ovarian sex cord stromal tumors.
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