发明授权
- 专利标题： Development of human monoclonal antibodies and uses thereof
- 专利标题（中）： 人单克隆抗体的开发及其用途
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申请号： US09040833申请日： 1998-03-18
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公开(公告)号： US06197582B1公开(公告)日： 2001-03-06
- 发明人: Ilya Trakht
- 申请人： Ilya Trakht
- 主分类号： C12N506
- IPC分类号： C12N506
摘要：
The present invention provides a trioma cell which does not produce any antibody obtained by fusing a hetermomyeloma cell which does not produce any antibody with a human lymphoid cell, wherein the heteromyeloma cell is designated B6B11. The invention also provides a tetroma cell capable of producing a monoclonal antibody having specific binding affinity for an antigen obtained by fusing a trioma cell which does not produce any antibody with a human lymphoid cell capable of producing antibody having specific binding affinity for the antigen. The invention also provides methods for generating trioma cells and tetroma cells, and the cells generated by the methods.
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