发明授权
US06211196B1 Benzyloxy-substituted, fused N-heterocycles, processes for their preparation, and their use as bradykinin receptor antagonists
失效
苄氧基取代的稠合N-杂环,其制备方法及其作为缓激肽受体拮抗剂的用途
- 专利标题: Benzyloxy-substituted, fused N-heterocycles, processes for their preparation, and their use as bradykinin receptor antagonists
- 专利标题(中): 苄氧基取代的稠合N-杂环,其制备方法及其作为缓激肽受体拮抗剂的用途
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申请号: US09048305申请日: 1998-03-26
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公开(公告)号: US06211196B1公开(公告)日: 2001-04-03
- 发明人: Holger Heitsch , Adalbert Wagner , Klaus Wirth , Bernward Schölkens
- 申请人: Holger Heitsch , Adalbert Wagner , Klaus Wirth , Bernward Schölkens
- 优先权: DE19712960 19970327
- 主分类号: C07D40100
- IPC分类号: C07D40100
摘要:
Benzyloxy-substituted, fused N-heterocycles, because of their ability to act as bradykinin receptor antagonists, have been found to be useful as therapeutics for the treatment and prevention of liver cirrhosis or Alzheimer's disease. This application describes such compounds, as well as processes for their preparation and use. The compounds according to this invention include compounds of formula (I) in which B, D, R1, and R2 have the meanings indicated herein.
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