发明授权
US06211386B1 Process for asymmetric hydrogenation 有权
不对称氢化方法

Process for asymmetric hydrogenation
摘要:
The present invention is a process for the preparation of a compound of the formula: where R3, R4 and n are defined in the specification which comprises hydrogenating a compound of the formula: the E-geometrical isomer thereof or a mixture of the Z- and E-isomers in the presence of catalyst containing Rh, a chiral ligand with at least one phosphorous atom where the hydrogenation is conducted in the presence of a base.
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