发明授权
US06217858B1 Pharmaceutical composition for treating hepatitis B virus (HBV) infection
失效
用于治疗乙型肝炎病毒（HBV）感染的药物组合物
- 专利标题： Pharmaceutical composition for treating hepatitis B virus (HBV) infection
- 专利标题（中）： 用于治疗乙型肝炎病毒（HBV）感染的药物组合物
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申请号： US08795473申请日： 1997-02-11
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公开(公告)号： US06217858B1公开(公告)日： 2001-04-17
- 发明人: Eithan Galun , Orit Nahor , Hubert E. Blum
- 申请人： Eithan Galun , Orit Nahor , Hubert E. Blum
- 主分类号： A61K4505
- IPC分类号： A61K4505
摘要：
The invention provides a pharmaceutical composition for the treatment of hepatitis B virus (HBV) infection, comprising an amount of a soluble active agent which interacts with at least one of the binding sites between hIL6 and pS1 and between hIL6 and hepatocytes and other HBV-permissive cells, the active agent being present in sufficient amount to competitively bind to at least one of the sites and thereby to prevent hIL6-mediated HBV infection of hepatocytes and other HBV-permissive cells.