发明授权
- 专利标题： Sugar-chain synthetase and process for producing the same
- 专利标题（中）： 糖链合成酶及其制备方法
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申请号： US09143438申请日： 1998-08-28
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公开(公告)号： US06218161B1公开(公告)日： 2001-04-17
- 发明人: Shuichi Tsuji , Nobuyuki Kurosawa , Toshiro Hamamoto , Young-Choon Lee , Takashi Nakaoka , Naoya Kojima
- 申请人： Shuichi Tsuji , Nobuyuki Kurosawa , Toshiro Hamamoto , Young-Choon Lee , Takashi Nakaoka , Naoya Kojima
- 优先权： JP5-348260 19931224; JP6-57369 19940328; JP6-91507 19940428
- 主分类号： C12N1554
- IPC分类号： C12N1554
摘要：
Novel GalNAc&agr;2,6-sialyltransferases P-B1 and P-B3; GalNAc&agr;2,6-sialyltransferase genes encoding the above GalNAc&agr;2,6-sialyltransferases P-B1 and P-B3; and an extracellularly releasable protein catalyzing GalNAc&agr;2,6-sialic acid transfer which comprises a polypeptide portion as being an active domain of the GalNAc&agr;2,6-sialyltransferase P-B1 or P-B3 together with a signal peptide are provided. Also provided is a process for preparing a sialyltransferases which enables efficient recovery of a sialyltransferase expressed in a large quantity in microorganisms.
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