发明授权
- 专利标题： Antibiotic formulation and use for bacterial infections
- 专利标题（中）： 抗生素配方和用于细菌感染
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申请号： US09407798申请日： 1999-09-28
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公开(公告)号： US06221388B1公开(公告)日： 2001-04-24
- 发明人: Evan M. Hersch , Eskild A. Petersen , Richard T. Proffitt , Kevin R. Bracken , Su-Ming Chiang
- 申请人： Evan M. Hersch , Eskild A. Petersen , Richard T. Proffitt , Kevin R. Bracken , Su-Ming Chiang
- 主分类号： A61K9127
- IPC分类号： A61K9127
摘要：
A liposomal aminoglycoside formulation comprising a neutral lipid, a negatively charged lipids and a sterol. The formulation contains unilamellar vesicles having an average size below 100 nm. A process of making liposomes containing an aminoglycoside is also provided. A method is also provided for the treatment of drug susceptible and drug resistant bacteria.
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