发明授权
- 专利标题: Sulfonamides as cell adhesion inhibitors
- 专利标题(中): 磺酰胺作为细胞粘附抑制剂
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申请号: US09424823申请日: 1999-11-29
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公开(公告)号: US06221888B1公开(公告)日: 2001-04-24
- 发明人: Philippe L. Durette , William K. Hagmann , Malcolm Maccoss , Sander G. Mills , Richard A. Mumford
- 申请人: Philippe L. Durette , William K. Hagmann , Malcolm Maccoss , Sander G. Mills , Richard A. Mumford
- 主分类号: A61K3118
- IPC分类号: A61K3118
摘要:
Compounds of Formula I are antagonists of VLA-4 and/or &agr;4&bgr;7, and as such are useful in the inhibition or prevention of cell adhesion and cell-adhesion mediated pathologies. These compounds may be formulated into pharmaceutical compositions and are suitable for use in the treatment of asthma, allergies, inflammation, multiple sclerosis, and other inflammatory and autoimmune disorders.
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