发明授权
- 专利标题： Gamma-ketoacid dipeptides as inhibitors of caspase-3
- 专利标题（中）： 伽马酮酸二肽作为半胱天冬酶-3的抑制剂
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申请号： US09526840申请日： 2000-03-16
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公开(公告)号： US06225288B1公开(公告)日： 2001-05-01
- 发明人: Yongxin Han , Andre Giroux , Erich Grimm , Renee Aspiotis , Sebastien Francoeur , Robert Zamboni , Petpiboon Prasit , Christopher Bayly , Dan McKay , Cameron Black
- 申请人： Yongxin Han , Andre Giroux , Erich Grimm , Renee Aspiotis , Sebastien Francoeur , Robert Zamboni , Petpiboon Prasit , Christopher Bayly , Dan McKay , Cameron Black
- 主分类号： C07K506
- IPC分类号： C07K506
摘要：
Compounds represented by formula I: as well as pharmaceutically acceptable salts, esters and hydrates thereof are disclosed along with pharmaceutical compositions and methods of treatment. The compounds are useful as inhibitors of caspase-3, which is implicated in modulating apoptosis.