发明授权
US06228880B1 4-amino-(ethylamino)-oxindole dopamine autoreceptor agonists
失效
4-氨基 - (乙基氨基) - 氧吲哚多巴胺自身受体激动剂
- 专利标题: 4-amino-(ethylamino)-oxindole dopamine autoreceptor agonists
- 专利标题(中): 4-氨基 - (乙基氨基) - 氧吲哚多巴胺自身受体激动剂
-
申请号: US09287675申请日: 1999-04-07
-
公开(公告)号: US06228880B1公开(公告)日: 2001-05-08
- 发明人: James A. Nelson , Mira A. Kanzelberger , Richard E. Mewshaw
- 申请人: James A. Nelson , Mira A. Kanzelberger , Richard E. Mewshaw
- 主分类号: A61K31404
- IPC分类号: A61K31404
摘要:
Compounds having dopaminegic activity are provided, having the formula: wherein R1 and R2 are each, independently, hydrogen, C1-10 alkyl, or (CH2)mR4, wherein R4 is phenyl or naphthyl which may be substituted by one or two substituents selected from the group consisting of C1-6 alkyl, halogen, C1-6 alkoxide and trifluoromethyl and m is 1 to 5; and R3 is hydrogen or C1-6 alkyl; or pharmaceutically acceptable salts thereof.
信息查询