发明授权
- 专利标题： Human monoclonal antibodies to epidermal growth factor receptor
- 专利标题（中）： 人表皮生长因子受体单克隆抗体
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申请号： US08851362申请日： 1997-05-05
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公开(公告)号： US06235883B1公开(公告)日： 2001-05-22
- 发明人: Aya Jakobovits , Xiao-Dong Yang , Michael Gallo , Xiao-Chi Jia
- 申请人： Aya Jakobovits , Xiao-Dong Yang , Michael Gallo , Xiao-Chi Jia
- 主分类号： C07K1628
- IPC分类号： C07K1628
摘要：
In accordance with the present invention, there are provided fully human monoclonal antibodies against human epidermal growth factor receptor (EGF-r). Nucelotide sequences encoding and amino acid sequences comprising heavy and light chain immunoglobulin molecules, particularly sequences corresponding to contiguous heavy and light chain sequences from CDR1 through CDR3, are provided. Hybridomas expressing such immunoglobulin molecules and monoclonal antibodies are also provided.
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