发明授权
US06242422B1 (Substituted)Acyl dipeptidyl inhibitors of the ice/ced-3 family of cysteine proteases
失效
(取代)半胱氨酸蛋白酶的冰/ ced-3家族的酰基二肽基抑制剂
- 专利标题: (Substituted)Acyl dipeptidyl inhibitors of the ice/ced-3 family of cysteine proteases
- 专利标题(中): (取代)半胱氨酸蛋白酶的冰/ ced-3家族的酰基二肽基抑制剂
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申请号: US09177546申请日: 1998-10-22
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公开(公告)号: US06242422B1公开(公告)日: 2001-06-05
- 发明人: Donald S. Karanewsky , Vincent J. Kalish , Edward D. Robinson , Brett R. Ullman
- 申请人: Donald S. Karanewsky , Vincent J. Kalish , Edward D. Robinson , Brett R. Ullman
- 主分类号: A61K3140
- IPC分类号: A61K3140
摘要:
This invention is directed to novel (substituted)acyl dipeptidyl ICE/ced-3 family inhibitor compounds. The invention is also directed to pharmaceutical compositions containing these compounds, as well as the use of such compositions in the treatment of patients suffering inflammatory, autoimmune and neurodegenerative diseases, for the prevention of ischemic injury, and for the preservation of organs that are to undergo a transplantation procedure.
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