Invention Grant
- Patent Title: Proteins involved in the regulation of cell—cell adhesion and uses thereof
- Patent Title (中): 涉及细胞粘附调节的蛋白质及其用途
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Application No.: US08874197Application Date: 1997-05-19
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Publication No.: US06245888B1Publication Date: 2001-06-12
- Inventor: James Martin Staddon
- Applicant: James Martin Staddon
- Priority: GB9423372 19941118
- Main IPC: C07K100
- IPC: C07K100

Abstract:
A protein, p100, is disclosed having a molecular weight of about 100 kDa, being associated in vivo with catenin-cadherin complex of epithelial or endothelial cells, and having cross-reactivity with an antibody to the p120 protein involved in cell-cell adhesion. Also disclosed is a method to treat a cancer or developmental disorder characterized by compromised cell-cell adhesion.
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