发明授权
- 专利标题： 5-(heterocyclic alkyl)-6-aryl-dihydropyrimidines
- 专利标题（中）： 5-（杂环烷基）-6-芳基 - 二氢嘧啶
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申请号： US09291553申请日： 1999-04-14
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公开(公告)号： US06248747B1公开(公告)日： 2001-06-19
- 发明人: Dhanapalan Nagarathnam , George Chiu , T. G. Murali Dhar , Wai C. Wong , Mohammad R. Marzabadi , Charles Gluchowski
- 申请人： Dhanapalan Nagarathnam , George Chiu , T. G. Murali Dhar , Wai C. Wong , Mohammad R. Marzabadi , Charles Gluchowski
- 主分类号： A61K31505
- IPC分类号： A61K31505
摘要：
This invention is directed to the use of dihydropyrimidine compounds, which are selective antagonists for cloned human &agr;1C receptors, for the treatment of benign prostatic hyperplasia and other diseases where antagonism of the human &agr;1C receptor is useful. The invention further provides a pharmaceutical composition comprising a therapeutically effective amount of the above-identified compounds and a pharmaceutically acceptable carrier.