发明授权
- 专利标题： Single-step method for labeling nucleic acids with mustard or aziridine labeling reagents
- 专利标题（中）： 用芥末或氮丙啶标记试剂标记核酸的单步方法
-
申请号： US08982485申请日： 1997-12-02
-
公开(公告)号： US06262252B1公开(公告)日： 2001-07-17
- 发明人: Jon A. Wolff , James E. Hagstrom , Paul Michael Slattum , Vladimir Budker
- 申请人： Jon A. Wolff , James E. Hagstrom , Paul Michael Slattum , Vladimir Budker
- 主分类号： C07H2100
- IPC分类号： C07H2100
摘要：
Compounds and methods are provided for a single-step covalent attachment of a label to a molecule comprising forming a covalently attachable labeling reagent for alkylating the molecule. Then, combining the covalently attachable labeling reagent with a mixture containing the molecule, under conditions wherein the labeling reagent has reactivity with the molecule thereby forming a covalent bond.
信息查询
