发明授权
- 专利标题： Thio-substituted pentanedioic acid derivatives
- 专利标题（中）： 硫代取代戊二酸衍生物
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申请号： US09228391申请日： 1999-01-12
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公开(公告)号： US06265609B1公开(公告)日： 2001-07-24
- 发明人: Paul F. Jackson , Keith M. Maclin , Eric Wang , Barbara S. Slusher , Rena Lapidus
- 申请人： Paul F. Jackson , Keith M. Maclin , Eric Wang , Barbara S. Slusher , Rena Lapidus
- 主分类号： C07C5502
- IPC分类号： C07C5502
摘要：
The present invention relate to thio-substituted pentanedioic acid derivatives that inhibit N-Acetylated &agr;-Linked Acidic Dipeptidase (NAALADase) enzyme activity, pharmaceutical compositions comprising the same, and methods of using the same to inhibit NAALADase enzyme activity, to effect neuronal activities, to inhibit angiogenesis, and to treat glutamate abnormalities, compulsive disorders and prostate diseases.
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