发明授权
- 专利标题: Combinatorial metabolic libraries
- 专利标题(中): 组合代谢库
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申请号: US09310398申请日: 1999-05-12
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公开(公告)号: US06268140B1公开(公告)日: 2001-07-31
- 发明人: W. Dorsey Stuart
- 申请人: W. Dorsey Stuart
- 主分类号: C12Q168
- IPC分类号: C12Q168
摘要:
The present invention provides methods and compositions for producing and screening combinatorial metabolic libraries of multimeric proteins. The present invention relies on the use of filamentous fingal heterokaryons that are produced using two or more parent strains into which a population of heterologous nucleic acids encoding components of a metabolic pathway have been introduced.
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