发明授权
- 专利标题： Imidazole derivatives having an inhibitory activity for farnesyl transferase and process for preparation thereof
- 专利标题（中）： 具有法呢基转移酶抑制活性的咪唑衍生物及其制备方法
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申请号： US09554646申请日： 2000-05-17
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公开(公告)号： US06268363B1公开(公告)日： 2001-07-31
- 发明人: Hyun Il Lee , Jong Sung Koh , Jin Ho Lee , Won Hee Jung , You Seung Shin , Hyun Ho Chung , Jong Hyun Kim , Seong Gu Ro , Tae Saeng Choi , Shin Wu Jeong , Tae Hwan Kwak , In Ae Ahn , Hyun Sung Kim , Sun Hwa Lee , Kwi Hwa Kim , Jung Kwon Yoo
- 申请人： Hyun Il Lee , Jong Sung Koh , Jin Ho Lee , Won Hee Jung , You Seung Shin , Hyun Ho Chung , Jong Hyun Kim , Seong Gu Ro , Tae Saeng Choi , Shin Wu Jeong , Tae Hwan Kwak , In Ae Ahn , Hyun Sung Kim , Sun Hwa Lee , Kwi Hwa Kim , Jung Kwon Yoo
- 优先权： KR97/63858 19971128; KR98/11359 19980331; KR98/23698 19980623; KR98/24423 19980626; KR98/31512 19980803; KR98/46457 19981030
- 主分类号： A61K314178
- IPC分类号： A61K314178
摘要：
The present invention relates to a novel imidazole derivative represented by formula (1) which shows an inhibitory activity against farnesyl transferase or pharmaceutically acceptable salts or isomers thereof, in which A, n1 and Y are defined in the specification; to a process for preparation of the compound of formula (1); to intermediates which are used in the preparation of the compound of formula (1); and to a pharmaceutical composition comprising the compound of formula (1) as an active ingredient.