发明授权
- 专利标题： PAI-1 determination and use thereof
- 专利标题（中）： PAI-1测定及其应用
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申请号： US08466965申请日： 1995-06-06
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公开(公告)号： US06271352B1公开(公告)日： 2001-08-07
- 发明人: Lars S. Nielsen , Peter Andreasen , Keld Dano , Nils Brunner
- 申请人： Lars S. Nielsen , Peter Andreasen , Keld Dano , Nils Brunner
- 优先权： DE3196/85 19850712
- 主分类号： C07K100
- IPC分类号： C07K100
摘要：
a monoclonal antibody which binds a human endothelial type plasminogen activator inhibitor (PAI-1) produced by dexamethasone-treated human HT-1080 fibrosarcoma cells may be used, inter alia, for determining PAI-1 protein abundance in tumor tissue or a sample of a body fluid. Measurements of this parameter may be useful in predicting the presence or metastasis of a tumor, or of predicting the progression of a known malignant tumor.
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