发明授权
- 专利标题: Preparation of alkali metal salts of L-ascorbic acid
- 专利标题(中): L-抗坏血酸的碱金属盐的制备
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申请号: US09688882申请日: 2000-10-17
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公开(公告)号: US06274744B1公开(公告)日: 2001-08-14
- 发明人: Wolfram Burst , Gerd Kaibel , Andreas Böttcher , Veronique Kessler , Thomas Kuntze
- 申请人: Wolfram Burst , Gerd Kaibel , Andreas Böttcher , Veronique Kessler , Thomas Kuntze
- 优先权: DE19954511 19991112
- 主分类号: C07D30762
- IPC分类号: C07D30762
摘要:
A process for preparing alkali metal salts of L-ascorbic acid comprising the following steps: a) esterifying 2-keto-L-gulonic acid or diacetone-2-keto-L-gulonic acid with a C1-C10-alkohol in the presence of an acid catalyst, b) rearranging the resultant 2-keto-L-gulonic acid C1-C10-alkyl ester in the presence of an alkali metal C1-C10-alkoxide, comprises carrying out each of the process steps a) and b) continuously.
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