发明授权
- 专利标题: Process for preparation of aromatic compounds
- 专利标题(中): 芳香族化合物的制备方法
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申请号: US09380598申请日: 1999-09-13
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公开(公告)号: US06274770B1公开(公告)日: 2001-08-14
- 发明人: James Hanley Clark , David Adams
- 申请人: James Hanley Clark , David Adams
- 优先权: GB9705159 19970313
- 主分类号: C07C4525
- IPC分类号: C07C4525
摘要:
There is disclosed a process for the preparation of a compound of general formula (I), wherein Y and Z each independently represent a fluorine atom or a hydroxy group, and a, b, c and d independently represent 0, 1, 2 or 3 provided that the sum of a, b, c, and d is 1, 2, 3 or 4; the process comprising treating a compound of general formula (II), wherein a, b, c, and d are as described above and L1 and L2 each independently represent an active group provided that either Y and L1 are different or Z and L2 are different, with a fluorinating system in the presence of oxygen. A preferred compound of general formula (I) is 4,4′-difluorobenzophenone which may be prepared from 4,4′-dinitrophenylmethane using tetramethylammonium fluoride.
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