发明授权
US06277877B1 Substituted n-(indole-2-carbonyl)glycinamides and derivates as glycogen phosphorylase inhibitors
失效
取代的n-（吲哚-2-羰基）甘氨酰胺和衍生物作为糖原磷酸化酶抑制剂
- 专利标题： Substituted n-(indole-2-carbonyl)glycinamides and derivates as glycogen phosphorylase inhibitors
- 专利标题（中）： 取代的n-（吲哚-2-羰基）甘氨酰胺和衍生物作为糖原磷酸化酶抑制剂
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申请号： US09638938申请日： 2000-08-15
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公开(公告)号： US06277877B1公开(公告)日： 2001-08-21
- 发明人: Dennis J. Hoover , Bernard Hulin , William H. Martin , Douglas Phillips , Judith L. Treadway
- 申请人： Dennis J. Hoover , Bernard Hulin , William H. Martin , Douglas Phillips , Judith L. Treadway
- 主分类号： A01N4338
- IPC分类号： A01N4338
摘要：
Compounds of Formula (I) wherein R6 is carboxy, (C1-C8)alkoxycarbonyl, benzyloxycarbonyl, C(O)NR8R9 or C(O)R12 as glycogen phosphorylase inhibitors, pharmaceutical compositions containing such inhibitors and the use of such inhibitors to treat diabetes, hyperglycemia, hypercholesterolemia, hypertension, hyperisulinemia, hyperlipidemia, atherosclerosis and myocardial ischemia in mammals.
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