发明授权
- 专利标题： Substituted bicyclic derivatives useful as anticancer agents
- 专利标题（中）： 用作抗癌剂的取代的双环衍生物
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申请号： US09488350申请日： 2000-01-20
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公开(公告)号： US06284764B1公开(公告)日： 2001-09-04
- 发明人: John Charles Kath , Norma Jacqueline Tom , Zhengyu Liu , Eric David Cox , Joel Morris , Samit Kumar Bhattacharya
- 申请人： John Charles Kath , Norma Jacqueline Tom , Zhengyu Liu , Eric David Cox , Joel Morris , Samit Kumar Bhattacharya
- 主分类号： A61K31517
- IPC分类号： A61K31517
摘要：
The invention relates to compounds of the formula 1 and to pharmaceutically acceptable salts and solvates thereof, wherein A, X, R1, R3 and R4 are as defined herein. The invention also relates to methods of treating abnormal cell growth in mammals with administering the compounds of formula 1 and to pharmaceutical compositions for treating such disorders which contain the compounds of formula 1. The invention also relates to methods of preparing the compounds of formula 1.