发明授权
- 专利标题： Rotavirus reassortant vaccine
- 专利标题（中）： 轮状病毒重配疫苗
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申请号： US09628289申请日： 2000-07-28
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公开(公告)号： US06290968B1公开(公告)日： 2001-09-18
- 发明人: H Fred Clark , Paul Offit , Stanley A. Plotkin
- 申请人： H Fred Clark , Paul Offit , Stanley A. Plotkin
- 主分类号： A61K3912
- IPC分类号： A61K3912
摘要：
The present invention provides novel rotavirus reassortants, vaccines employing the novel reassortants and methods for their preparation and administration. One such reassortant contains the gene encoding the v.p.7 neutralization antigen of a human rotavirus. Another reassortant contains the gene encoding the v.p.4 neutralization antigen of a human rotavirus. The remaining genes are provided solely from the bovine rotavirus WC3 strain, or from both the human and bovine strains.
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