发明授权
US06297259B1 Substituted N-methyl-N-(4-(piperidin-1-yl)-2-(aryl)butyl) benzamides useful for the treatment of allergic diseases
失效
用于治疗过敏性疾病的N-取代的N-甲基-N-（4-（哌啶-1-基）-2-（芳基）丁基）苯甲酰胺
- 专利标题： Substituted N-methyl-N-(4-(piperidin-1-yl)-2-(aryl)butyl) benzamides useful for the treatment of allergic diseases
- 专利标题（中）： 用于治疗过敏性疾病的N-取代的N-甲基-N-（4-（哌啶-1-基）-2-（芳基）丁基）苯甲酰胺
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申请号： US09328964申请日： 1999-06-09
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公开(公告)号： US06297259B1公开(公告)日： 2001-10-02
- 发明人: George P. Maynard , John M. Kane , Larry D. Bratton , Elizabeth M. Kudlacz
- 申请人： George P. Maynard , John M. Kane , Larry D. Bratton , Elizabeth M. Kudlacz
- 主分类号： A61K31445
- IPC分类号： A61K31445
摘要：
The present invention relates to novel substituted N-methyl-N-(4-(piperidin-1-yl)-2-(aryl)butyl)benzamide derivatives of the formula stereoisomers thereof, and pharmaceutically acceptable salts thereof which are useful as histamine receptor antagonists and tachykinin receptor antagonists. Such antagonists are useful in the treatment of allergic rhinitis, including seasonal rhinitis and sinusitis; inflammatory bowel diseases, including Crohn's disease and ulcerative colitis; asthma; bronchitis; and emesis.