发明授权
US06300338B1 Tricyclic carbamate compounds useful for inhibition of g-protein function and for treatment of proliferative diseases
失效
可用于抑制g-蛋白功能和治疗增殖性疾病的三环氨基甲酸酯化合物
- 专利标题： Tricyclic carbamate compounds useful for inhibition of g-protein function and for treatment of proliferative diseases
- 专利标题（中）： 可用于抑制g-蛋白功能和治疗增殖性疾病的三环氨基甲酸酯化合物
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申请号： US09348916申请日： 1999-07-07
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公开(公告)号： US06300338B1公开(公告)日： 2001-10-09
- 发明人: W. Robert Bishop , Ronald J. Doll , Alan K. Mallams , F. George Njoroge , Joanne M. Petrin , John J. Piwinski , Ronald L. Wolin , Arthur G. Taveras , Stacy W. Remiszewski
- 申请人： W. Robert Bishop , Ronald J. Doll , Alan K. Mallams , F. George Njoroge , Joanne M. Petrin , John J. Piwinski , Ronald L. Wolin , Arthur G. Taveras , Stacy W. Remiszewski
- 主分类号： A61K31435
- IPC分类号： A61K31435
摘要：
A method of inhibiting Ras function and therefore inhibiting cellular growth is disclosed. The method comprises the administration of a compound of Formula 1.0 Also disclosed are novel compounds of the formulas: Also disclosed are processes for making 3-substituted compounds of the Formulas 1.1, 1.2 and 1.3. Further disclosed are novel compounds which are intermediates in the processes for making the 3-substituted compounds of Formulas 1.1, 1.2, and 1.3.
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