发明授权
- 专利标题: Effector proteins of Rapamycin
- 专利标题(中): 雷帕霉素的效应蛋白
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申请号: US08471112申请日: 1995-06-06
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公开(公告)号: US06313264B1公开(公告)日: 2001-11-06
- 发明人: Thomas J. Caggiano , Yanqiu Chen , Amedeo A. Failli , Katherine L. Molnar-Kimber , Koji Nakanishi
- 申请人: Thomas J. Caggiano , Yanqiu Chen , Amedeo A. Failli , Katherine L. Molnar-Kimber , Koji Nakanishi
- 主分类号: C07K1700
- IPC分类号: C07K1700
摘要:
This invention comprises novel Rapamycin-FKBP12 binding proteins of mammalian origin for identification, design and synthesis of immunomodulatory, anti-restenosis or anti-tumor agents, as well as fragments of the proteins and the DNA, cDNA, antisense RNA and DNA segments corresponding to the proteins. This invention also comprises methods for isolating the proteins and therapeutic uses related to the proteins.
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