发明授权
US06316026B1 Method and apparatus for manufacturing tablet capable of quick disintegration in oral cavity
有权
用于制造能够在口腔中快速分解的片剂的方法和装置
- 专利标题: Method and apparatus for manufacturing tablet capable of quick disintegration in oral cavity
- 专利标题(中): 用于制造能够在口腔中快速分解的片剂的方法和装置
-
申请号: US09227921申请日: 1999-01-08
-
公开(公告)号: US06316026B1公开(公告)日: 2001-11-13
- 发明人: Mitsutoshi Tatara , Koji Matsunaga , Toshihito Shimizu
- 申请人: Mitsutoshi Tatara , Koji Matsunaga , Toshihito Shimizu
- 优先权: JP10-267789 19980922
- 主分类号: A61K920
- IPC分类号: A61K920
摘要:
A method and an apparatus are adapted to manufacture a tablet capable of quick disintegration in the oral cavity that has a sufficiently large porosity and can be disintegrated in the oral cavity in a very short period of time, typically between 3 and 5 seconds. A tablet manufactured by means of such a method and such an apparatus also constitutes part of the present invention. The method for manufacturing a tablet capable of quickly disintegration in the oral cavity comprises steps of punching a tablet out of a pharmaceutical composition containing one or more than one medicinal agents and one or more than one water-soluble saccharides under pressure between 0.20 and 0.01 t/cm2 and shaping the tablet by moisturizing and drying it, while transferring it without causing it to drop, said tablet having a porosity between 20 and 40%.
信息查询