发明授权
US06316217B1 Activin receptor-like kinases, proteins having serine threonine kinase domains and polynucleotides encoding same
失效
活化素受体样激酶,具有丝氨酸苏氨酸激酶结构域的蛋白质和编码其的多核苷酸
- 专利标题: Activin receptor-like kinases, proteins having serine threonine kinase domains and polynucleotides encoding same
- 专利标题(中): 活化素受体样激酶,具有丝氨酸苏氨酸激酶结构域的蛋白质和编码其的多核苷酸
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申请号: US08436265申请日: 1995-10-30
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公开(公告)号: US06316217B1公开(公告)日: 2001-11-13
- 发明人: Kohei Miyazono , Peter ten Dijke , Petra Franzen , Hidetoshi Yamashita , Carl-Henrik Heldin
- 申请人: Kohei Miyazono , Peter ten Dijke , Petra Franzen , Hidetoshi Yamashita , Carl-Henrik Heldin
- 优先权: GB9224057 19921117; GB9304677 19930308; GB9304680 19930308; GB9311047 19930528; GB9313763 19930702; GB9316099 19930803; GB9321344 19931015
- 主分类号: C12P2106
- IPC分类号: C12P2106
摘要:
A new receptor family has been identified, of activin-like kinases. Novel proteins have activin/TGF-&bgr;-type I receptor functionality, and have consequential diagnostic/therapeutic utility. They may have a serine/threonine kinase domain, a DFKSRN or DLKSKN sequence in subdomain VIB and/or a GTKRYM sequence in subdomain VIII.
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