发明授权
- 专利标题： Nucleic acids encoding kappa opioid receptors
- 专利标题（中）： 编码κ阿片受体的核酸
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申请号： US08292694申请日： 1994-08-19
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公开(公告)号： US06319686B1公开(公告)日： 2001-11-20
- 发明人: Graeme I. Bell , Terry Reisine , Kazuki Yasuda
- 申请人： Graeme I. Bell , Terry Reisine , Kazuki Yasuda
- 主分类号： C12P2106
- IPC分类号： C12P2106
摘要：
The invention relates generally to compositions of and methods for obtaining opioid receptor polypeptides. The invention relates as well to polynucleotides encoding opioid receptor polypeptides. More specifically, the invention relates to polynucleotides encoding kappa opioid receptor polypeptides, the recombinant vectors carrying those sequences, the recombinant host cells including either the sequences or vectors, and recombinant opioid receptor polypeptides. By way of example, the invention discloses the cloning and functional expression of at least three different opioid receptor polypeptides. The invention includes as well, methods for using the isolated, recombinant receptor polypeptides in assays designed to select and improve substances capable of interacting with opioid receptor polypeptides for use in diagnostic, drug design and therapeutic applications.