发明授权
- 专利标题： 23484, A novel human ubiquitin protease
- 专利标题（中）： 23484，一种新型人类泛素蛋白酶
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申请号： US09408865申请日： 1999-09-30
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公开(公告)号： US06329171B1公开(公告)日： 2001-12-11
- 发明人: Rosana Kapeller-Libermann
- 申请人： Rosana Kapeller-Libermann
- 主分类号： C12N1512
- IPC分类号： C12N1512
摘要：
The present invention relates to a newly identified human ubiquitin protease belonging to the family of mammalian deubiquitinating enzymes. The invention also relates to polynucleotides encoding the ubiquitin protease. The invention further relates to methods using the ubiquitin protease polypeptides and polynucleotides as a target for diagnosis and treatment in ubiquitin-mediated or -related disorders. The invention further relates to drug-screening methods using the ubiquitin protease polypeptides and polynucleotides to identify agonists and antagonists for diagnosis and treatment. The invention further encompasses agonists and antagonists based on the ubiquitin protease polypeptides and polynucleotides. The invention further relates to procedures for producing the ubiquitin protease polypeptides and polynucleotides.
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