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US06333327B2 Method for the treatment of Multiple Sclerosis 失效
多发性硬化症的治疗方法

  • 专利标题: Method for the treatment of Multiple Sclerosis
  • 专利标题(中): 多发性硬化症的治疗方法
  • 申请号: US09784302
    申请日: 2001-02-16
  • 公开(公告)号: US06333327B2
    公开(公告)日: 2001-12-25
  • 发明人: Lennart MöllerJan Bergman
  • 申请人: Lennart MöllerJan Bergman
  • 主分类号: A61K31495
  • IPC分类号: A61K31495
Method for the treatment of Multiple Sclerosis
摘要:
Use of a compound of formula I wherein R1 represents hydrogen or one or several, preferably 1 to 4, similar or different substituents in the positions 1-4 and/or 7-10, selected from halogen, preferably Br, lower alkyl/alkoxy group having not more than 4 carbon atoms, trifluoromethyl group, trichloromethyl group; and in one of the positions 7-10 R1 can be a hydroxyl group; X is a group —(CH2)n—R2, wherein R2 represents a nitrogen containing basic residue such as NH2, NHR4 or NR5R6, wherein R4, R5 and R6 independently are lower alkyl or cycloalkyl and n is an integer of from 1 to 4 and R3 represents hydrogen, lower alkyl/cycloalkyl group having not more than 4 carbon atoms, and the physiologically acceptable addition products of the compounds with acids and halogen adducts, preferably adducts with iodine, iodine monochloride or iodine monobromide, for preparing a drug for treatment of MS (multiple sclerosis).
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