发明授权
US06333349B1 Sulfonamide-substituted fused 7-membered ring compounds, their use as a medicament, and pharmaceutical preparations comprising them
失效
磺酰胺取代的稠合的7-元环化合物，它们作为药物的用途，以及包含它们的药物制剂
- 专利标题： Sulfonamide-substituted fused 7-membered ring compounds, their use as a medicament, and pharmaceutical preparations comprising them
- 专利标题（中）： 磺酰胺取代的稠合的7-元环化合物，它们作为药物的用途，以及包含它们的药物制剂
-
申请号： US09342597申请日： 1999-06-29
-
公开(公告)号： US06333349B1公开(公告)日： 2001-12-25
- 发明人: Joachim Brendel , Hans Jochen Lang , Uwe Gerlach
- 申请人： Joachim Brendel , Hans Jochen Lang , Uwe Gerlach
- 优先权： DE19707656 19970226
- 主分类号： A61K31335
- IPC分类号： A61K31335
摘要：
The present invention relates to compounds of formula I, in which X1, X2, X3, X4, Y1, Y2, Y3, Y4, R(3), R(4) and R(5) have the meanings mentioned in the specification, their preparation and their use, in particular in pharmaceuticals. The compounds effect the potassium channel or the IKs channel opened by cyclic adenosine monophosphate (cAMP) and are outstandingly suitable as pharmaceutical active compounds, for example for the prophylaxis and therapy of cardiovascular disorders, in particular arrhythmias, for the treatment of ulcers of the gastrointestinal region or for the treatment of diarrheal disorders.
信息查询
