发明授权
- 专利标题： Death domain containing receptor 4 nucleic acids and methods
- 专利标题（中）： 含有受体4核酸的死亡域和方法
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申请号： US09013895申请日： 1998-01-27
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公开(公告)号： US06342363B1公开(公告)日： 2002-01-29
- 发明人: Jian Ni , Craig A. Rosen , James G. Pan , Reiner L. Gentz , Vishva M. Dixit
- 申请人： Jian Ni , Craig A. Rosen , James G. Pan , Reiner L. Gentz , Vishva M. Dixit
- 主分类号： G01N3353
- IPC分类号： G01N3353
摘要：
The present invention relates to novel Death Domain Containing Receptor-4 (DR4) proteins which are members of the tumor necrosis factor (TNF) receptor family. In particular, isolated nucleic acid molecules are provided encoding the human DR4 proteins. DR4 polypeptides are also provided as are vectors, host cells and recombinant methods for producing the same. The invention further relates to screening methods for identifying agonists and antagonists of DR4 activity.
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