发明授权
- 专利标题： A33 antigen specific immunoglobulin products and uses thereof
- 专利标题（中）： A33抗原特异性免疫球蛋白产品及其用途
-
申请号： US09425638申请日： 1999-10-22
-
公开(公告)号： US06342587B1公开(公告)日： 2002-01-29
- 发明人: Carlos F. Barbas, III , Christoph Rader , Gerd Ritter , Sydney Welt , Lloyd J. Old
- 申请人： Carlos F. Barbas, III , Christoph Rader , Gerd Ritter , Sydney Welt , Lloyd J. Old
- 主分类号： C07K1628
- IPC分类号： C07K1628
摘要：
The invention is directed to novel CDRs and immunoglobulin products that bind to A33 antigens and methods for their use. The invention also involves a method for making humanized antibodies, using a rabbit as a host animal, and phage display library methodologies, and the antibodies themselves. The methodology is useful, for example, in generating humanized antibodies against molecules associated with cancer, such as A33, which is associated with colon cancer.
信息查询
