发明授权
- 专利标题： Substituted piperidines as melanocortin-4 receptor agonists
- 专利标题（中）： 取代的哌啶作为黑皮质素-4受体激动剂
-
申请号： US09585111申请日： 2000-06-01
-
公开(公告)号： US06350760B1公开(公告)日： 2002-02-26
- 发明人: Raman K. Bakshi , Khaled J. Barakat , Ravi P. Nargund , Brenda L. Palucki , Arthur A. Patchett , Iyassu Sebhat , Zhixiong Ye , Leonardus H. T. Van Der Ploeg
- 申请人： Raman K. Bakshi , Khaled J. Barakat , Ravi P. Nargund , Brenda L. Palucki , Arthur A. Patchett , Iyassu Sebhat , Zhixiong Ye , Leonardus H. T. Van Der Ploeg
- 主分类号： A61K3144
- IPC分类号： A61K3144
摘要：
Certain novel substituted piperidine compounds are agonists of the human melanocortin receptor(s) and, in particular, are selective agonists of the human melanocortin-4 receptor (MC-4R). They are therefore useful for the treatment, control, or prevention of diseases and disorders responsive to the activation of MC-4R, such as obesity, diabetes, sexual dysfunction, including erectile dysfunction and female sexual dysfunction. Also provided are methods of treating sexual dysfunction with a compound that is a selective agonist of MC-4R over any other human melanocortin receptor.
信息查询
