发明授权
- 专利标题: Vasopressin antagonist formulation and process
- 专利标题(中): 血管加压素拮抗剂配方及方法
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申请号: US09668883申请日: 2000-09-25
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公开(公告)号: US06352718B1公开(公告)日: 2002-03-05
- 发明人: Joseph K. Yoon , Richard W. Saunders , Mahdi Fawzi
- 申请人: Joseph K. Yoon , Richard W. Saunders , Mahdi Fawzi
- 主分类号: A61K964
- IPC分类号: A61K964
摘要:
This invention provides novel formulations for N-[4-(5H-pyrrolo[2,1-c][1,4]benzodiazepin-10(11H)ylcarbonyl)-3-chlorophenyl]-5-fluoro-2-methyl-benzamide, or a pharmaceutically acceptable salt thereof, and processes for making them, the formulations comprising from about 1% to about 20% of active ingredient, from about 1% to about 18% of a surfactant component, from about 50% to about 80% of a component of one or more polyethylene glycols, from about 1% to about 20% of a component of one or more sucrose fatty acid esters and/or polyvinylpyrrolidone and, optionally, one or more pharmaceutically acceptable preservatives or antioxidants
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