发明授权
- 专利标题: Therapeutic agents
- 专利标题(中): 治疗剂
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申请号: US09748153申请日: 2000-12-27
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公开(公告)号: US06353002B2公开(公告)日: 2002-03-05
- 发明人: Alan Martin Birch , Paul Anthony Bradley
- 申请人: Alan Martin Birch , Paul Anthony Bradley
- 优先权: GB9704948 19970311
- 主分类号: A61K31445
- IPC分类号: A61K31445
摘要:
Compounds of formula I and pharmaceutically acceptable salts thereof in which A is methylene or —O—; B is methylene or —O—; G1—G2—G3 form a heteroaromatic or heteroaliphatic chain; g is 0, 1 or 2; U is an alkylene chain optionally substituted by one or more alkyl; Q represents a divalent group containing nitrogen atoms; and T is an optionally substituted aryl or heteroaryl group, have utility in the treatment of central nervous system disorders, for example depression, anxiety, psychoses (for example schizophrenia), tardive dyskinesia, Parkinson's disease, obesity, hypertension, Tourette's syndrome, sexual dysfunction, drug addiction, drug abuse, cognitive disorders, Alzheimer's disease, senile dementia, obsessive-compulsive behaviour, panic attacks, social phobias, eating disorders and anorexia, cardiovascular and cerebrovascular disorders, non-insulin dependent diabetes mellitus, hyperglycaemia, constipation, arrhythmia, disorders of the neuroendocrine system, stress, and spasticity.
公开/授权文献
- US20010008903A1 Therapeutic agents 公开/授权日:2001-07-19