A liquid chromatograph and a column packing material effectively condensing cationic specimen and exhibiting a high resolution. The liquid chromatograph includes a pre-focusing column (30, 40) having a volume of less than 2.0 milliliters and packed with a column packing material, in which a porous support is coated by a silicone polymer having a Si—R—X (R is a spacer part, X is a sulfonic group) bond and a Si—R′ (R′ is a hydrophilic group) bond, wherein the specimen to be analyzed is supplied to the pre-focusing column in the state dispersed in a solvent for condensation. The condensed specimen is then separated in a separation column (16, 43) used for separating the specimen dispersed in the solvent, and the separated specimen is analyzed by a detector (17, 41).