发明授权
- 专利标题: Aerosol compositions
- 专利标题(中): 气溶胶成分
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申请号: US09029863申请日: 1998-04-22
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公开(公告)号: US06361760B1公开(公告)日: 2002-03-26
- 发明人: Saburo Murata , Fumio Shiomojo , Yuji Tokunaga , Takehisa Hata
- 申请人: Saburo Murata , Fumio Shiomojo , Yuji Tokunaga , Takehisa Hata
- 优先权: JP7-239342 19950919
- 主分类号: A61K912
- IPC分类号: A61K912
摘要:
The use of a medium-chain fatty acid triglyceride as the dispersant in the preparation of a medicinal aerosol composition comprising tricyclic compound (I) dispersed in a liquefied hydrofluoroalkane propellant is described. When a liquefied hydrofluoroalkane is added to a kneaded premix of the tricyclic compound (I) and a medium-chain fatty acid triglyceride, the active ingredient is evenly dispersed in the liquefied hydrofluoroalkane. Therefore, by distributing a dispenser first with the kneaded premix and, then, with a liquefied hydrofluoroalkane under cooling or elevated pressure, there can be provided a medicinal aerosol composition having an improved uniformity of content of the active ingredient.
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