发明授权
US06362201B1 3-cyclopropyl and 3-cyclobutyl pyrrolidine modulators of chemokine receptor activity
失效
3-环丙基和3-环丁基吡咯烷调节剂的趋化因子受体活性
- 专利标题: 3-cyclopropyl and 3-cyclobutyl pyrrolidine modulators of chemokine receptor activity
- 专利标题(中): 3-环丙基和3-环丁基吡咯烷调节剂的趋化因子受体活性
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申请号: US09516775申请日: 2000-03-01
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公开(公告)号: US06362201B1公开(公告)日: 2002-03-26
- 发明人: Robert K. Baker , William H. Parsons , Kathleen Rupprecht
- 申请人: Robert K. Baker , William H. Parsons , Kathleen Rupprecht
- 主分类号: A61K31445
- IPC分类号: A61K31445
摘要:
The present invention is directed to pyrrolidine compounds of the formula I: (wherein R1, R2, R3, R4c, R4d, and R4f are defined herein) which are useful as modulators of chemokine receptor activity. In particular, these compounds are useful as modulators of the chemokine receptors CCR-3 and/or CCR-5.
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