A control method of a hydraulic pressure source-driving type vehicle hydraulic brake system is provided in which water hammering or worsening of the brake feeling does not occur when brake liquid is replenished through a replenish passage. A motor for driving a pump is actuated at a full driving force with an on-off valve in the brake liquid replenish passage opened in the stage in which the hydraulic pressure difference between the master cylinder pressure and the brake hydraulic pressure is small. Also, in the stage in which the brake hydraulic pressure is increased, so that the hydraulic pressure difference from the master cylinder hydraulic pressure has entered a predetermined range, a solenoid valve in the replenish passage is closed to return to the normal control in which the driving force of the motor is controlled so as to correspond to the hydraulic pressure difference.