发明授权
- 专利标题： Therapeutic suppression of specific immune response by administration of oligomeric forms of antigen of controlled chemistry
- 专利标题（中）： 通过施用受控化学的抗原的寡聚形式来治疗性地抑制特异性免疫应答
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申请号： US08440331申请日： 1995-05-12
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公开(公告)号： US06375951B1公开(公告)日： 2002-04-23
- 发明人: Howard M. Dintzis , Renée Z. Dintzis , James K. Blodgett , John C. Cheronis , Gary Kirschenheuter
- 申请人： Howard M. Dintzis , Renée Z. Dintzis , James K. Blodgett , John C. Cheronis , Gary Kirschenheuter
- 主分类号： A61K3900
- IPC分类号： A61K3900
摘要：
The invention features a non-immunogenic construct for reducing a non-primary antibody response to an epitope of a T-dependent antigen. The construct is free of high molecular weight immunostimulatory molecules and contains copies of the epitope which bind to a B cell membrane immunoglobulin receptor specific for the epitope but fail to form an imnunon.
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