发明授权
- 专利标题: Cyclic amidines useful as NMDA NR2B antagonists
- 专利标题(中): 作为NMDA NR2B拮抗剂有用的环脒
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申请号: US09550972申请日: 2000-04-17
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公开(公告)号: US06376530B1公开(公告)日: 2002-04-23
- 发明人: Christopher F. Claiborne , Nigel J. Liverton , David A. Claremon
- 申请人: Christopher F. Claiborne , Nigel J. Liverton , David A. Claremon
- 主分类号: C07D20944
- IPC分类号: C07D20944
摘要:
The invention encompasses novel compounds of Formula I as well as a method of treating NMDA mediated diseases comprising administration to a patient in need of such treatment a non-toxic amount of a compound of Formula I effective to block the NMDA NR2B receptor sub-unit. The invention also encompasses certain pharmaceutical compositions for the treatment of NMDA mediated diseases comprising compounds of Formula I and a pharmaceutically acceptable carrier.
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