发明授权
- 专利标题: Intravascular delivery of non-viral nucleic acid
- 专利标题(中): 非病毒核酸的血管内递送
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申请号: US09450315申请日: 1999-11-29
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公开(公告)号: US06379966B2公开(公告)日: 2002-04-30
- 发明人: Sean D. Monahan , Jon A. Wolff , Paul M. Slattum , James E. Hagstrom , Vladimir G. Budker , David B. Rozema
- 申请人: Sean D. Monahan , Jon A. Wolff , Paul M. Slattum , James E. Hagstrom , Vladimir G. Budker , David B. Rozema
- 主分类号: C12N1585
- IPC分类号: C12N1585
摘要:
Disclosed is a complex for providing nucleic acid expression in a cell. A polynucleotide and a polymer are mixed together to form the complex wherein the zeta potential of the complex is not positive. Then the complex is delivered to the cell wherein the nucleic acid is expressed.
公开/授权文献
- US20010019723A1 INTRAVASCULAR DELIVERY OF NON-VIRAL NUCLEIC ACID 公开/授权日:2001-09-06
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