A multi-channel audio speaker system is provided for use with a desktop personal computer. This system includes a cabinet having a bottom surface for placement upon a desktop and having a top surface for supporting a computer monitor. Left front, center front and right front speakers are housed in the cabinet along with two sub-woofer speakers. Left rear and right rear speakers are provided in separate remote cabinets. The primary cabinet includes an amplifier having seven channels of amplification. The system is provided for use with a multi-channel audio source such as Dolby® 5.1 format, which provides five channels of full range audio data which are directed to the first five channels of amplification and then to the front and rear speakers. The sixth channel of low frequency audio data is split and directed to the sixth and seventh amplification channels which are in turn directed to the two sub-woofer systems. A by-pass inlet signal conductor may also be provided so that the speaker system can be utilized with alternative sound sources such as a conventional high fidelity receiver.