发明授权
- 专利标题: Method for serial analysis of gene expression
- 专利标题(中): 基因表达序列分析方法
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申请号: US09107228申请日: 1998-06-30
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公开(公告)号: US06383743B1公开(公告)日: 2002-05-07
- 发明人: Kenneth W. Kinzler , Bert Vogelstein , Victor E. Velculescu , Lin Zhang
- 申请人: Kenneth W. Kinzler , Bert Vogelstein , Victor E. Velculescu , Lin Zhang
- 主分类号: C12Q168
- IPC分类号: C12Q168
摘要:
Serial analysis of gene expression, SAGE, a method for the rapid quantitative and qualitative analysis of transcripts is provided. Short defined sequence tags corresponding to expressed genes are isolated and analyzed. Sequencing of over 1,000 defined tags in a short period of time (e.g., hours) reveals a gene expression pattern characteristic of the function of a cell or tissue. Moreover, SAGE is useful as a gene discovery tool for the identification and isolation of novel sequence tags corresponding to novel transcripts and genes.
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