发明授权
US06384071B2 Taxoids, their preparation and pharmaceutical compositions containing them
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紫杉烷类,它们的制备方法和含有它们的药物组合物
- 专利标题: Taxoids, their preparation and pharmaceutical compositions containing them
- 专利标题(中): 紫杉烷类,它们的制备方法和含有它们的药物组合物
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申请号: US09759449申请日: 2001-01-16
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公开(公告)号: US06384071B2公开(公告)日: 2002-05-07
- 发明人: Hervé Bouchard , Jean-Dominique Bourzat , Alain Commercon
- 申请人: Hervé Bouchard , Jean-Dominique Bourzat , Alain Commercon
- 优先权: FR9214813 19921209
- 主分类号: A61K31337
- IPC分类号: A61K31337
摘要:
New taxoids of general formula (I), their preparation, and pharmaceutical compounds containing them. In general formula (I), for example, Ar represents an aryl radical, R represents an alkoxyacetyl radical, R1 represents a benzoyl radical or a radical of formula R2—O—CO— in which R2 represents an optionally substituted alkyl radical, an alkenyl, alkynyl, cycloalkyl, cycloalkenyl, bicycloalkyl, phenyl or heterocyclyl radical. The new products of general formula (I) have a remarkable antitumor activity.
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