- 专利标题： Pyrrolidine modulators of chemokine receptor activity
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申请号： US09542898申请日： 2000-04-04
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公开(公告)号： US06399619B1公开(公告)日： 2002-06-04
- 发明人: Scott Berk , Charles G. Caldwell , Kevin T. Chapman , Jeffrey Hale , Christopher Lynch , Malcolm MacCoss , Sander G. Mills , Christopher Willoughby
- 申请人： Scott Berk , Charles G. Caldwell , Kevin T. Chapman , Jeffrey Hale , Christopher Lynch , Malcolm MacCoss , Sander G. Mills , Christopher Willoughby
- 主分类号： A61K31495
- IPC分类号： A61K31495
摘要：
The present invention is directed to pyrrolidine compounds of the formula I: (wherein R1, R2, R3, R4, R5, R6 and n are defined herein) which are useful as modulators of chemokine receptor activity. In particular, these compounds are useful as modulators of the chemokine receptors CCR-5 and/or CCR-3.
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